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Greiner Bio-one has developed a system of 3D Cell Culture tools to open new dimensions and allow the processing of a 3D cell culture in a fast and easy 2D workflow. The core technology of Greiner Bio-One’s Magnetic 3D Cell Culture is the magnetization of cells with biocompatible NanoShuttle™-PL. The reproducible formation of one spheroid per well in an F-bottom plate with Cell-Repellent surface is forced by magnets either by levitation or bioprinting, to form structurally and biologically representative 3D models in-vitro. There are many advantages of the magnetic 3D cell culture (m3D) technology. This technology provides reproducible spheroid formation in a scalable 6 Well to 1536 Well format that can be performed on a flat surface optimal for high-resolution microscopy and HTS. Rapid 3D culture formation within 24 hours for most cell types and easy media changes and co-culture of different cell types. This technology is compatible with fluorescence microscopy, Western blotting, qRT-PCR, Flow Cytometry, viability assays, chemiluminescence, and the list goes on.

A recent article published in Frontiers in Genetics from a team led by senior author Professor Vivaldo Moura-Neto reviews current understanding about the interplay between hypoxia, miRNAs, stem-like cells, and cancer aggressiveness. Contributing to cancer aggressiveness is an interconnected role between microRNAs, stem-like cancer cells, and the hypoxic microenvironment. Since tumor oxygen levels play a critical role in promoting malignant progression, therapeutic resistance, and metastatic potential; cancer scientists add physiologic relevance to in vitro studies by simulating tumor hypoxia.

With the new range of Pipettes and Tips for the 384-Well Plate System this is manual pipetting into 384-well plates made easy! The new pipette/pipette tip system optimized for 384-well plates provide a high level of reproducibility and user safety. Start up to 24 reactions simultaneously. Extraordinary fine tip shape and coaxiality for safe plate maneuverings. Tedious alternate well pipetting with 8- or 12-channel pipettes is not necessary anymore with 16-/24-channel pipettes. Process complete columns or rows in just one step. Increase efficiency by 50% reduction of pipetting steps.

A Memmert constant climate offers an intuitive and easy-to-use operating menu and high-quality, corrosion-resistant and easily cleanable stainless steel, as well as a wide range of options for programming and documentation using interfaces, integrated data logger and AtmoCONTROL software. Three years guarantee worldwide direct from Memmert and our Lab Supply exclusive service support. With practical applications in environment simulation, long term material tests, seed germination, plant cultivation and breeding insects, zebra fish and reptiles. Four model sizes to choose from, including the new HPP400.

FaPEx is the acronym for Fast Pesticides Extraction.It’s an innovative, simple and fast method for the preparation of samples, a crucial step preceding LC/MS/MS or GC/MS/MS analysis. More than simply increasing yields of extraction, reducing time and costs associated with pesticide separation, FaPEx also scales down labour time, glassware requirements, specialised equipment and laboratory space requirement. It also significantly diminishes the amount of waste solvents and other chemicals.

Versatile 600 W to 10kW circulation chillers used between -20 and 40°C for dissipating process heat in laboratories, mini plants and production facilities

CONSTANT CLIMATE CHAMBER HPP They are simply unbeatable in energy efficiency. Furthermore, as constant climate chambers HPP have a very long, almost maintenance free service life, they are perfectly suited for stability tests, storage in con trolled environment and conditioning. The high precision temperature control as well as the active humidification and dehumidification were particularly adapted to the ICH guidelines, option Q1A, for stability tests.

3D Spheroid Bioprinting - Watch a Video showing the setup by Greiner Bio-one here!

The new AP series 4 & 5 decimal place balances

The LAUDA LOOP is a peltier circulation thermostats for external temperature control