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Mitomycin C from Streptomyces caespitosus

Product Code: MERM4287-2MG

CAS No: 50-07-7
Merck Website Link

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Overview
Mitomycin C from Streptomyces caespitosus powder, BioReagent, suitable for cell culture

General description
Mitomycin C is a systemic chemotherapy compound and an antibiotic obtained from Streptomyces caespitosus.[1][2] It is the first bioreductive alkylating agent to be identified and is a derivative of 3-amino-5-hydroxybenzoic acid (AHBA), D-glucosamine, L-methionine and carbamoyl phosphate.[3]
Chemical structure: Aziridine

Application
Mitomycin C from Streptomyces caespitosus has been used for the treatment of feeder layers such as, PMEF (primary mouse embryonic fibroblasts) and CD1 mouse embryonic fibroblasts (MEFs) for the culture of hESCs (human embryonic stem cells).[4][5][6] It has also been used for the treatment of BLC (basal-like cancer) cell line.[7]
Technical Specifications
Supplier Merck
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