From the use of organoids and spheroids as an experimental platform in 3D bioprinting, to the simulation of the tumour microenvironment, cell-based studies are benefitting from better 3D model systems.
The core technology of Greiner Bio-One’s Magnetic 3D Cell Culture is the magnetisation of cells with NanoShuttle-PL. The magnetised cells can be aggregated by magnetic forces, either by levitation or bioprinting, to form microphysiologically relevant 3D models in vitro. The magnetic system overcomes the limitations of other platforms by enabling the manipulation of cells for the rapid formation of spheroids, reproducible and scalable in size for high throughput, without restrictions of cell type.
3D in a 2D workflow
Reproducible spheroid formation
Scalable – 6 Well to 1536 Well
Performed on a flat surface optimal for high-resolution microscopy and HTS
Rapid 3D culture formation within 24 hours for most cell types
No specialized equipment or media
Easy media changes and co-culture of different cell types
Compatible with fluorescence microscopy, Western blotting, qRT-PCR, Flow Cytometry, viability assays, chemiluminescence, etc.
Ready for automation
Biocompatible nanoparticles to magnetise cells
Spheroid formation by magnetic levitation, bioprinting or printings of rings.
In this video see how creating spheroids can be a simple process using Greiner Bio-One’s m3D cell culture products, making 3D cultures as easy as 2D.
3D cell culture can save you time, hassle, and money when developing models for preclinical studies and testing, as well as for researching and developing new therapies. Numerous research papers have shown that 3D cell cultures can accurately predict the efficacy or toxicity of drug treatments. Growing cells in 3D can reveal a realistic drug response, gene expression and cell behaviour, capture phenotypic heterogeneity and mimic tumour microenvironments.
Find out more about 3D cell cuture and browse a range of Greiner Bio-One products.
Stay up-to-date on the latest science using 3D cell culture technologies.
For product pricing and availability, please contact us at info@labsupply.co.nz